Preedakorn Chunhacha

Assistant Professor

Email ORCID

Education

  • PhD in Pharmaceutical Sciences (Pharmacology and Physiology) | Chulalongkorn University, Thailand


Experience

  • Present | Assistant Professor | Department of Biochemistry and Microbiology, Chulalongkorn University

การศึกษา

  • ปรัชญาดุษฎีบัณฑิต สาขาวิทยาศาสตร์เภสัชกรรม (เภสัชวิทยาและสรีรวิทยา) | จุฬาลงกรณ์มหาวิทยาลัย ประเทศไทย


ประสบการณ์

  • ปัจจุบัน | ผู้ช่วยศาสตราจารย์ | ภาควิชาชีวเคมีและจุลชีววิทยา จุฬาลงกรณ์มหาวิทยาลัย

Preedakorn’s Publications

ผลงานตีพิมพ์ของPreedakorn

Roles of caveolin-1 on anoikis resistance in non small cell lung cancer.
Preedakorn Chunhacha, Pithi Chanvorachote
PubMed , 3 , 149 - 55 (2012)

Acquired resistance to chemotherapy in lung cancer cells mediated by prolonged nitric oxide exposure.
Piyaparisorn Wongvaranon, Varisa Pongrakhananon, Preedakorn Chunhacha, Pithi Chanvorachote
PubMed , 12 , 5433 - 44 (2013)

Effects of artonin e on migration and invasion capabilities of human lung cancer cells.
Kanok Plaibua, Varisa Pongrakhananon, Preedakorn Chunhacha, Boonchoo Sritularak, Pithi Chanvorachote
PubMed , 8 , 3079 - 88 (2013)

Long-Term Nitric Oxide Exposure Enhances Lung Cancer Cell Migration
Arpasinee Sanuphan, Preedakorn Chunhacha, Varisa Pongrakhananon, Pithi Chanvorachote
BioMed Research International , 1 - 9 (2013)

Prolonged Nitric Oxide Exposure Enhances Anoikis Resistance and Migration through Epithelial-Mesenchymal Transition and Caveolin-1 Upregulation
Pithi Chanvorachote, Varisa Pongrakhananon, Preedakorn Chunhacha
BioMed Research International , 1 - 10 (2014)

Imperatorin sensitizes anoikis and inhibits anchorage-independent growth of lung cancer cells
Kanuengnit Choochuay, Preedakorn Chunhacha, Varisa Pongrakhananon, Rataya Luechapudiporn, Pithi Chanvorachote
Journal of Natural Medicines , 3 , 599 - 606 (2012)

Anoikis: A Potential Target to Prevent Lung Cancer Metastasis?
Pithi Chanvorachote, Preedakorn Chunhacha, Varisa Pongrakhananon
Lung Cancer Management , 3 , 169 - 171 (2013)

Epithelial-mesenchymal transition mediates anoikis resistance and enhances invasion in pleural effusion-derived human lung cancer cells
Preedakorn Chunhacha, Virote Sriuranpong, Pithi Chanvorachote
Oncology Letters , 3 , 1043 - 1047 (2013)

Caveolin-1 Regulates Endothelial Adhesion of Lung Cancer Cells via Reactive Oxygen Species-Dependent Mechanism
Pithi Chanvorachote, Preedakorn Chunhacha
PLoS ONE , 2 , e57466 - e57466 (2013)

Corrigendum to “Long-Term Nitric Oxide Exposure Enhances Lung Cancer Cell Migration”
Arpasinee Sanuphan, Preedakorn Chunhacha, Varisa Pongrakhananon, Pithi Chanvorachote
BioMed Research International , 1 - 1 (2015)

Neuritogenic effect of standardized extract of Centella asiatica ECa233 on human neuroblastoma cells
Oraphan Wanakhachornkrai, Varisa Pongrakhananon, Preedakorn Chunhacha, Aree Wanasuntronwong, Anusara Vattanajun, Boonyong Tantisira, Pithi Chanvorachote, Mayuree H. Tantisira
BMC Complementary and Alternative Medicine , 1 , 204 - 204 (2013)

Ouabain Suppresses the Migratory Behavior of Lung Cancer Cells
Varisa Pongrakhananon, Preedakorn Chunhacha, Pithi Chanvorachote
PLoS ONE , 7 , e68623 - e68623 (2013)

Expression of CA125 and cisplatin susceptibility of pleural effusion-derived human lung cancer cells from a Thai patient
Pithi Chanvorachote, Sudjit Luanpitpong, Preedakorn Chunhacha, Worrawat Promden, Virote Sriuranpong
Oncology Letters , 2 , 252 - 256 (2012)

Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells
Preedakorn Chunhacha, Varisa Pongrakhananon, Yon Rojanasakul, Pithi Chanvorachote
American Journal of Physiology-Cell Physiology , 9 , C1284 - C1292 (2012)

Caveolin-1 induces lamellipodia formation via an Akt-dependent pathway
Pithi Chanvorachote, Preedakorn Chunhacha, Varisa Pongrakhananon
Cancer Cell International , 1 , 52 - 52 (2014)

Artonin E mediates MCL1 down-regulation and sensitizes lung cancer cells to anoikis.
Ekkarat Wongpankam, Preedakorn Chunhacha, Varisa Pongrakhananon, Boonchoo Sritularak, Pithi Chanvorachote
PubMed , 12 , 5343 - 51 (2012)

Anticancer and antimetastatic activities of Renieramycin M, a marine tetrahydroisoquinoline alkaloid, in human non-small cell lung cancer cells.
Hasseri Halim, Preedakorn Chunhacha, Khanit Suwanborirux, Pithi Chanvorachote
PubMed , 1 , 193 - 201 (2011)

Lung Cancer Metastasis
Pithi Chanvorachote, Preedakorn Chunhacha
Elsevier eBooks , 61 - 76 (2017)

Silymarin inhibits cisplatin-mediated apoptosis via inhibition of hydrogen peroxide and hydroxyl radical generation
Angkana Tantituvanont, Pacharaporn Jiamchaisri, Preedakorn Chunhacha, Kanittha Pongjit, Chuanpit Ninsontia, Kulwara Meksawan, Boonchoo Sritularak, Pithi Chanvorachote
DOAJ (DOAJ: Directory of Open Access Journals) (2015)

Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death
Decha Pinkaew, Abhijnan Chattopadhyay, Matthew D. King, Preedakorn Chunhacha, Zhihe Liu, Heather L. Stevenson, Yanjie Chen, Patuma Sinthujaroen, Owen M. McDougal, Ken Fujise
Nature Communications , 1 , 18 - 18 (2017)

Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel
Hasseri Halim, Decha Pinkaew, Preedakorn Chunhacha, Patuma Sinthujaroen, Perumal Thiagarajan, Ken Fujise
PLoS ONE , 6 , e0218934 - e0218934 (2019)

Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure
Preedakorn Chunhacha, Decha Pinkaew, Patuma Sinthujaroen, Dawn E. Bowles, Ken Fujise
Cell Death Discovery , 1 , 310 - 310 (2021)

GRP78/BiP determines senescence evasion cell fate after cisplatin-based chemotherapy
Zin Zin, Kanuengnit Choochuay, Alisa Tubsuwan, Decha Pinkaew, Maneewan Suksomtip, Chanida Vinayanuwattikun, Pithi Chanvorachote, Preedakorn Chunhacha
Scientific Reports , 1 , 22448 - 22448 (2021)

Potential Natural Product Derived Compounds for Lung Cancer Therapy
Pithi Chanvorachote, Pilaiwanwadee Hutamekalin, Preedakorn Chunhacha, Zin Zin
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects , 1 - 44 (2022)

Saccharothrix obliqua sp. nov., isolated from soil of Sichang Island, Thailand
Md Abul Kalam Azad, Preedakorn Chunhacha, Chanwit Suriyachadkun, Paranee Sripreechasak, Somboon Tanasupawat, Wongsakorn Phongsopitanun
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY , 8 (2022)

Cisplatin Induces Senescent Lung Cancer Cell-Mediated Stemness Induction via GRP78/Akt-Dependent Mechanism
Nicharat Sriratanasak, Preedakorn Chunhacha, Zin Zin, Pithi Chanvorachote
Biomedicines , 11 , 2703 - 2703 (2022)

Potential roles of hyaluronic acid in in vivo CAR T cell reprogramming for cancer immunotherapy
Chawee Laomeephol, Sudartip Areecheewakul, Supannikar Tawinwung, Koramit Suppipat, Preedakorn Chunhacha, Nuno M. Neves, Jittima Amie Luckanagul
Nanoscale , 48 , 17821 - 17840 (2022)

Potential Natural Product–Derived Compounds for Lung Cancer Therapy
Pithi Chanvorachote, Pilaiwanwadee Hutamekalin, Preedakorn Chunhacha, Zin Zin
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects , 209 - 252 (2022)

N-Containing α-Mangostin Analogs via Smiles Rearrangement as the Promising Cytotoxic, Antitrypanosomal, and SARS-CoV-2 Main Protease Inhibitory Agents
Nan Yadanar Lin Pyae, Arnatchai Maiuthed, Wongsakorn Phongsopitanun, Bongkot Ouengwanarat, Warongrit Sukma, Nitipol Srimongkolpithak, Jutharat Pengon, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan, Zin Zin, Preedakorn Chunhacha, Patcharin Wilasluck, Peerapon Deetanya, Kittikhun Wangkanont, Kowit Hengphasatporn, Yasuteru Shigeta, Thanyada Rungrotmongkol, Supakarn Chamni
Molecules , 3 , 1104 - 1104 (2023)

Resveratrol Shows Potent Senescence Reversal in Experimental Cellular Models of Particular Matter 2.5-induced Cellular Senescence in Human Dermal Papilla Cells
Zin Zin, Thunwadee Srithawirat, Preedakorn Chunhacha, Chatchai Chaotham, Wanatchaporn Arunmanee, PREEYAPHAN PHOOKPHAN, Pithi Chanvorachote
In Vivo , 2 , 665 - 673 (2024)

Kinetics and correlation of caveolin-1 and MCL-1 proteins with lung cancer cell anoikis
Preedakorn Chunhacha, Pithi Chanvorachote

Substituents introduction of methyl and methoxy functional groups on resveratrol stabilizes mTOR binding for autophagic cell death induction
Zin Zin, Satapat Racha, Preedakorn Chunhacha, Masashi Yokoya, Sohsuke Moriue, Hongbin Zou, Pithi Chanvorachote
Scientific Reports , 1 , 14675 - 14675 (2025)

Fortilin deficiency induces anti-atherosclerotic phenotypes in macrophages and protects hypercholesterolemic mice against atherosclerosis
Nattaporn Wanachottrakul, Decha Pinkaew, Sandipan Mukherjee, Preedakorn Chunhacha, Mari Nakashima, Asa A. Brockman, Uttariya Pal, Hasseri Halim, Yuhong Wei, Lena Tanaka, Hanna Huynh, Kota V. Ramana, Shi‐You Chen, Rebecca A. Ihrie, Ken Fujise
Communications Biology , 1 , 1040 - 1040 (2025)

Targeting mTOR Signaling in Cancer: The Promise of Natural Product-derived Inhibitors
P. Chanvorachote, Chatchai Chaotham, Zin Zin, Preedakorn Chunhacha
Anticancer Research , 2 , 553 - 568 (2026)

Methoxy and Ketone Substitutions of Resveratrol Enhance Its Anticancer Activity by Increasing MEK and ERK Binding Affinity in Colorectal Cancer Cells
PATTHARAPORN SAELIM, Zin Zin, Satapat Racha, Masashi Yokoya, RIKAKO YAMASHITA, Preedakorn Chunhacha, Pithi Chanvorachote
Anticancer Research , 4 , 1957 - 1966 (2026)

Cypripedin Induces Apoptosis and Synergizes with Bortezomib via ER Stress Mediated Ubiquitination of GRP78 in T-Cell Acute Lymphoblastic Leukemia
Zin Zin, Bodee Nutho, Boonchoo Sritularak, Pithi Chanvorachote, Preedakorn Chunhacha
Molecules , 11 , 1823 - 1823 (2026)
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